Binding Characterization

Our scientific team has broad experience in designing a new protocol for binding characterization using biophysical techniques as:

  • Surface Plasmon Resonance (SPR).
  • MicroScale Thermophoresis (MST).
  • Isothermal Titration Calorimetry (ITC).
  • Nuclear Magnetic Resonance (NMR)

as well as computational simulations for:

  • Docking.
  • Molecular Dynamics (MD).

Data analysis

We develop our own analytical tools for accurate and reliable analysis of biophysical data. We are specialized in

  • Mechanism of interaction elucidation
  • Characterization of complex binding
  • Kinetic and thermodynamic coherence in multi-technique studies.

Our analysis can cover a large range of different complex interactions:

  • Multisite binding
  • Cooperativity interactions
  • Conformational changes
  • Competition experiments

Software Development

We develop ad hoc software for automatization of acquisition, analysis and store in a database of experimental data. We can optimize your Drug Discovery projects by saving time and money.

Contact us if you are interested in software for:

  • Micellization
  • Screening using Differential Scanning Fluorescence
  • Ranking drug candidate through one-single ITC injection